MACOFAR E liquid filling

Sterile liquid filling line. MACOFAR E includes a series of washers, depyrogenation tunnels and liquid filling machines to configure the perfect aseptic liquid filling line for vials intended for injection.

Sterile liquid filling turnkey solution up to external decontamination machine.

Selection of preset configurations for sterile liquid filling matching the needs of the pharmaceutical industry.

100 % tare/gross check weighing system with automatic filling adjustment.

Zero loss logic end-of-batch procedure.

• Up to 24,000 vials/hour.
• System for < 3 % oxygen residues inside vials.
• Ergonomic vial loading.
• Full visibility of the entire process and each washing step.
• Segregation of filler from tunnel for SIP.
• Cost-effective solution.

Oftalmica liquid filling machine

Sterile liquid filling and capping. The Oftalmica machine’s main application is filling and capping of ophthalmic products. Additionally, it can easily handle nasal sprays and injectables (small formats). Minimised change-over parts and downtime due to wide adaptability range of transport system and machine stations. Dosing system designed according to ophthalmic production needs – capable to maintain high speed/max. output even with viscous and foamy liquids which need to be fed into bottles with small mouths.

Available also as turnkey solution with washer and tunnel.

• Max. 12,000 bottle/hour.
• Camera for cap verification.
• Dosing system with 8 singularly motorised pumps.
• Multiple capping.
• Torque control.

LVI Series for liquid filling

Sterile and non-sterile liquid filling and capping. Compact versatility for complex products: LVI machines can be equipped with different types of liquid filling technologies and capping options. Suitable to handle a wide range of pharmaceutical liquid products. The machine can also be equipped with laminar flow and environmental controls for aseptic processes.

• Up to 6,000 bottles/hour.
• Compact design.
• Torque control on capping unit.
• Nitrogen flushing.
• Up to two double capping stations inside machine body.
• Downstream C.W. integration.
• Viable and non-vaible particles monitoring.

MicroRobot 50 powder/liquid filling

Robotic powder/liquid filling machine for small batches under isolation technology. The MicroRobot 50 can be configured for powder and/or liquid filling (combi filling) under isolation technology – even of high potency drugs and extremely difficult to fill powders. Size parts-free robots manage all operations and vials transfer. Filling, stoppering and capping all in one machine. Capable of handling oxygen-sensitive products due to a system to reduce oxygen level below 3 %.

• Maximum 3,000 vials/hour with minimum dosage: 20 mg / 0.5 ml.
• Format-free robotic transport.
• In case of missing alu cap, robot re-performs closing operation, all vials leave the machine completely sealed.
• 100 % check weighing system in the filling area.
• Powder filling unit designed to handle also hygroscopic / irregular types of powders.
• 100 % sealing force verification.
• Vial transport via size parts-free Stericlean robots.
• Verification of presence and position of rubber stopper vai camera with zero loss logic, robots ready to perform correct stoppering before proceeding with next steps.

MicroMaxX Series for sterile powder filling

High speed sterile powder filling and stoppering. Double powder dosing station machine with highly ergonomic supply of product components in aseptic environment. Vacuum-pressure technology, integrated check weighing system and rubber stoppering by means of pick and place with verification of cap presence are some of the key features of MicroMaxX Series. Easy tool-free replacement of product contact parts from machine front side. Up to two different types of powders filled into the same vial. Unique LEV design to minimise powder dispersion in the filling area. Suitable for oxygen-sensitive products due to system for reducing oxygen level below 3 %.

• Up to 24,000 vials/hour with a filling range (single shot per dosing disc) of 30 mg to 1,500 mg.
• Environmental monitoring points positioned according to dedicated risk analysis.
• 100 % in line high speed tare/gross check weighing system.
• Two dosing stations to fill two different types of powder into the same vial.
• Verification of rubber stoppers presence and position by means of camera.
• Rubber stoppers are applied on vials by means of pick and place.
• Compact footprint.
• Ergonomic handling of components.

Micro Series for powder filling

Sterile powder filling and closing of glass vials. Available as monoblock configuration including powder filling, stoppering and capping up to 6,000 vials per hour, or as a pure filling and stoppering system up to 18,000 vials per hour. Micro series features vacuum-pressure dosing technology to accurately fill powder into glass vials. Machines can be equipped with check weighing unit, environmental controls and pre-loading of packaging materials to handle sterile productions at best. Highly reliable vacuum pressure dosing system suitable for steady production and big batches. Two dual disc stations for double powder filling with statistical check weighing before and after each dosage available on demand.

• Up to 18,000 vials/hour with a filling range of 50 mg to 1,500 mg.
• Integrated alu-capping unit, separated from the filling area.
• Vacuum-pressure dosing disc with in-line tare/gross statical check weighing system.
• Minimised powder residues at the end of batch due to special hopper.
• System to reduce oxygen level in vials below 3 % available.
• Compact design for minimum footprint in the cleanroom.
• Cost-effective solution.

MAC Series for alu capping

Sterile alu capping of vials. MAC machines are designed for aseptic processes and top-quality sealing of vials. Alu caps are sealed by moving the vials from below, ensuring the highest quality and preventing scratches or defects. Secure closing of vials thanks to dedicated idle blade and upper vial contrast, which is optionally equipped with loading cell to continuously monitor sealing force. Optimised machine layout to avoid contamination from aluminum particles potentially caused by the caps feeding bowl.

• Cap pressence check.
• Sealing unit designed for high-speed, high quality capping.
• Loading cells available for sealing force verification and subsequent adjustment.
• Verification of presence of rubber stoppers before sealing.